TomoTherapy® and Radixact™ Technology

Unrivaled Capabilities

In use since 2002, the TomoTherapy® System is designed to safely and routinely deliver image-guided, intensity modulated radiation therapy (IG-IMRT) for the treatment of cancer and other diseases. What has made the TomoTherapy System stand out when compared to conventional radiation systems is the integration of a computed tomography (CT) scanner to perform daily imaging before each treatment session. The daily imaging capability makes it possible for clinicians to identify and correct for any variations in patient positioning, changes in the tumor or in other factors, such as weight gain or loss, to ensure the continued precise and safe delivery of the radiation dose to the target area.

Because the TomoTherapy System's precision minimizes the exposure of radiation to surrounding healthy tissue, many doctors report that their patients suffer from fewer side effects compared to patients receiving conventional forms of radiation therapy. The precision may enable the TomoTherapy System to be used to treat patients who have had radiation therapy before, if their cancers have returned.

The Radixact® Treatment Delivery System is the next generation TomoTherapy platform, designed to enable doctors to more efficiently and effectively deliver precise radiation treatments to more patients.

Helical Delivery

Built on a foundation that resembles CT scanner-like imaging, the TomoTherapy and Radixact Systems are open, wide, circular structures through which a patient, resting comfortably on a treatment table, receives radiation treatments.

The ring design enables the Systems to support helical delivery of treatment – which means that radiation can be delivered from 360 degrees around the patient's body. The Systems also use thousands of smaller radiation beams, referred to as “beamlets” – compared to larger beams of conventional systems – to deliver different doses of radiation to the tumor from a variety of angles around the body. These beamlets, combined with the unique helical delivery method, enable clinicians to deliver a more customized and precise treatment plan, and minimize exposure of healthy surrounding tissue.

Helical delivery capabilities also enable treatment of a full range of diseases, including larger, more complex tumors; multiple tumors; recurrent tumors and cancers of the skin and blood.

One-of-a-Kind Treatment Technology for Multiple Cancers

Radiation oncologists have treated many types of cancers with the TomoTherapy System, ranging from routine cancers to complex tumors, including, but not limited to:

  • Brain cancers and benign brain tumors
  • Head, neck and oral cancers
  • Breast cancers, including inflammatory breast disease
  • Lung cancers and lung tumors
  • Skin cancers
  • Prostate cancer, from early stage to advanced disease
  • Esophageal and upper gastrointestinal cancers
  • Cervical, ovarian, uterine, vaginal and vulva cancers
  • Colon, stomach, rectal and anal cancers
  • Liver and pancreatic cancers
  • Cancers that have metastasized to multiple locations
  • Pre-transplant treatment for blood diseases, such as leukemia

The TomoTherapy and Radixact Systems are capable of delivering classic 3D radiation when that is all that is required. But they were designed to deliver intensity modulated radiation therapy (IMRT) so that the beams can be varied for better dosing to the shape of the patient's tumor. Increasingly, TomoTherapy also is being used for hypofractionated therapy, enabling higher doses to be precisely and safely delivered in fewer treatment sessions.

A good example of the precision and unique capabilities of the TomoTherapy System is its use in clinical trials for a hippocampal-sparing technique during whole brain radiation. This approach is being done to spare the memory aspect of the brain, while providing radiation treatment to the rest of the brain.

1. Radiation therapy is completely non-invasive. In some cases, tiny gold markers (fiducials) that help distinguish the tumor from non-cancerous soft tissue are implanted with a minimally invasive procedure.